1415963-60-8

Basic information

• Product Name: OseltaMivir Acid Hydrochloride
• Synonyms: OseltaMivir Acid Hydrochloride;Oseltamivir carboxylate hydrochloride;OTBMMOBYSNFNOE-UHFFFAOYSA-N
• CAS NO: 1415963-60-8
• Molecular Formula: C₁₄H₂₄N₂O₄*ClH
• Molecular Weight: 320.8123
• Mol File: 1415963-60-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: OseltaMivir Acid Hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: OseltaMivir Acid Hydrochloride(1415963-60-8)
• EPA Substance Registry System: OseltaMivir Acid Hydrochloride(1415963-60-8)

Safety Data

• Hazardous Substances Data: 1415963-60-8(Hazardous Substances Data)

Usage

Uses

Oseltamivir Acid Hydrochloride is a metabolite of Oseltamivir (O701000), an orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug. It is a COVID19-related research product.

Upstream product

• 764639-63-6 (3R,4R,5S)-4-acetamido-5-[(tert-butoxycarbonyl)-amino]-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid 
• 204255-11-8 oseltamivir phosphate 

Relevant articles and documents

Discovery of a series of novel compounds with moderate anti-avian H5N1 influenza virus activity in chick embryo

Enlightened by some flavonoid compounds, which had been found as influenza neuraminidase inhibitors, we designed and synthesized a series of novel compounds containing different amino acid fragments. We also reported a simple synthetic route from oseltamivir to prepare its active form which was used as the positive control. The result of enzyme inhibition assay indicated that all the designed compounds displayed weak inhibitory activity against neuraminidase. However, they showed moderate anti-avian H5N1 influenza virus activity in chick embryo. Besides interfering with the function of neuraminidase, these compounds seemed to inhibit the replication of influenza virus by some other mechanism which deserved deep study.