1415964-87-2Relevant academic research and scientific papers
New pyrazolo-quinoline scaffold as a reversible colorimetric fluorescent probe for selective detection of Zn2+ ions and its imaging in live cells
Kasirajan, Gayathri,Krishnaswamy, Velmurugan,Raju, Nandhakumar,Mahalingam, Malathi,Sadasivam, Mathusalini,Palathurai Subramaniam, Mohan,Ramasamy, Shankar
, p. 136 - 145 (2017)
A simple colorimetric fluorescent chemosensor 1-[5-(2-chloro-6-methylquinolin-3-yl)-3-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one (L) based on pyrazoline has been designed, synthesized and characterized. The sensing properties of L were studied using UV–visible and fluorescence spectrophotometric analyses. L showed excellent selectivity towards Zn2+ ions over other metal ions in aqueous media through “OFF-ON” type process and a possible photoinduced electron transfer (PET). The viability of L to Zn2+ has been demonstrated by live cell imaging.
Synthesis of new quinoline-2-pyrazoline-based thiazolinone derivatives as potential antimicrobial agents
Desai,Joshi,Rajpara
, p. 3663 - 3674 (2013/07/26)
A series of 2-(5-(2-chloro-6-methylquinolin-3-yl)-3-(aryl)-4,5-dihydro-1H- pyrazol-1-yl)thiazol-4(5H)ones (4a-l) were synthesized and characterized by IR, 1H NMR, 13C NMR, and mass spectra. All the synthesized compounds were tested for their in vitro antimicrobial activity against Escherichia coli (MTCC 443), Pseudomonas aeruginosa (MTCC 1688), Staphylococcus aureus (MTCC 96), Streptococcus pyogenes (MTCC 442), Candida albicans (MTCC 227), Aspergillus niger (MTCC 282), and Aspergillus clavatus (MTCC 1323) by serial broth dilution. Compounds 4e, 4f, 4g, 4i, 4j, and 4l were the most distinctive derivatives identified in present study because of their remarkable in vitro antimicrobial potency.
