1415975-98-2Relevant articles and documents
Focused library development of 2-phenylacrylamides as broad spectrum cytotoxic agents
Tarleton, Mark,Dyson, Lauren,Gilbert, Jayne,Sakoff, Jennette A.,McCluskey, Adam
, p. 333 - 347 (2013/02/22)
With our lead compound (E)-3-(4-chlorophenyl)-2-(1H-pyrrole-2-carbonyl) acrylonitrile (1) inducing 50% growth inhibition of 11 cancer cell lines at 27-61 μM, potency enhancements were rapidly established through the synthesis of a series of focused compou
