1415981-79-1 Usage
General Description
Boc-NH-PEG12-CH2CH2COOH is a chemical compound consisting of a Boc-protected amine group, a polyethylene glycol (PEG) chain with 12 repeat units, and a carboxylic acid functional group. The Boc group serves as a protecting group for the amine, allowing for selective deprotection under specific reaction conditions. The PEG chain provides water solubility and biocompatibility, making the compound useful for applications in drug delivery and bioconjugation. The carboxylic acid group can participate in chemical reactions such as amidation and esterification, further expanding the potential applications of the compound in various fields of chemistry and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 1415981-79-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,1,5,9,8 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1415981-79:
(9*1)+(8*4)+(7*1)+(6*5)+(5*9)+(4*8)+(3*1)+(2*7)+(1*9)=181
181 % 10 = 1
So 1415981-79-1 is a valid CAS Registry Number.
1415981-79-1Relevant articles and documents
Synthesis of carboxy-polyethylene glycol-amine (CA (PEG)n) and [1-14C]-CA (PEG)n via oxa-Michael addition of amino-polyethylene glycols to propiolates vs to acrylates
Song, Fengbin,Chen, Lu,Lin, Ronghui,Salter, Rhys
, p. 15 - 24 (2019/12/30)
Synthesis of carboxy-polyethylene glycol-amine (CA (PEG)n) via oxa-Michael addition of amino-polyethylene glycols to either acrylates or propiolates was investigated. Compared with the oxa-Michael addition to acrylates, the corresponding addition to propiolates was found to proceed under mild reaction conditions and afford the adducts in high yields from a broad scope of substrates. A two-step efficient and convenient synthesis of benzyl [1-14C]-propiolate from 14CO2 was therefore developed and utilized as a common synthon to afford practical and high yielding access to [1-14C]-CA (PEG)n.
