1415995-67-3Relevant academic research and scientific papers
Syntheses of phenoxyalkyl esters of 3,30-bis(indolyl)methanes and studies on their molecular properties from single crystal XRD and DFT techniques
Suresh Kumar,Antony Muthu Prabu,Jegan Jenniefer,Bhuvanesh,Thomas Muthiah,Kumaresan
, p. 109 - 120 (2013/10/22)
An efficient solvent-free synthesis of phenoxyalkyl esters of bis(indolyl)methanes (BIMs) from indole and formylphenoxyalkyl esters using potassium titanyl oxalate and the molecular properties of these BIMs using DFT method are described here. Structure o
An efficient one pot syntheses of aryl-3,3′-bis(indolyl)methanes and studies on their spectral characteristics, DPPH radical scavenging-, antimicrobial-, cytotoxicity-, and antituberculosis activity
Suresh Kumar,Kumaresan,Antony Muthu Prabhu,Bhuvanesh,Seethalakshmi
supporting information, p. 254 - 263 (2013/02/23)
An efficient one-pot syntheses of aryl-3,3′-bis(indolyl)methanes (BIMs) from indole/2-methylindole and formylphenoxyaliphatic acid(s) is described. Esterification of carboxylic acid and aromatic electrophilic substitution reactions are achieved simultaneous in the presence of potash alum as a catalyst. This catalyst could be recovered and reused without substantial loss in its catalytic activity and the methodology could be applied on a range of closely related substrates. The solvation characteristics in ground and excited states of the compounds by monitoring the absorbance and fluorescence band maxima have been studied. The fluorescence studies in protic and aprotic solvents were rationalized on the basis of solute-solvent interaction and substituents effect on these photophysical processes analyzed. The compounds prepared showed efficient antimicrobial effect against human pathogens, cytotoxicity against A431 cell line, and DPPH radical scavenging effect. Single crystal XRD studies have been carried out for a few compounds synthesized in this work.
