14161-85-4Relevant academic research and scientific papers
Catalytic Alkyne Arylation Using Traceless Directing Groups
Park, Jung-Woo,Kang, Bubwoong,Dong, Vy M.
, p. 13598 - 13602 (2018/09/25)
By using Pd0/Mandyphos, we achieved a three-component aminoarylation of alkynes to generate enamines, which are then hydrolyzed to either α-arylphenones or α,α-diarylketones. This Pd-catalyzed method overcomes established known pathways to enable the use of amines as traceless directing groups for C?C bond formation.
