141610-87-9

Upstream product

• 19980-35-9 1-trimethylsilyloxy-2-methyl-1-cyclohexene 
• 152429-15-7 (S)-2-Methyl-2-[(R)-1-methyl-2-((1S,2R,6S,7R)-7,10,10-trimethyl-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-en-4-yl)-ethyl]-cyclohexanone 

Relevant academic research and scientific papers

Enantioselective Synthesis of (+)-De-Isopropenyl Nootkatone

The absolute configuration of the δ-oxo acid 11, obtained through an asymmetric Michael-type reaction involving the activated chiral α,β-unsaturated oxazoline 7, was established by comparison of the CD curves of the derived (+)-octalone 14 and (+)-nootkat

Asymmetric michael reactions : Enantioselective synthesis of δ-oxo-acids

β-substituted and α,β-disubstituted δ-oxo acids are synthesized with high enantiomeric excess from chiral 2-propenyl oxazolines 8 and 11, whilst 2-vinyl oxazlines 7 and 10 are less efficient asymmetric inductors.