1416150-75-8Relevant academic research and scientific papers
Cooperative heterogeneous organocatalysis and homogeneous metal catalysis for the one-pot regioselective synthesis of 2-pyridones
Allais, Christophe,Basle, Olivier,Grassot, Jean-Marie,Fontaine, Maxime,Anguille, Stephane,Rodriguez, Jean,Constantieux, Thierry
, p. 2084 - 2088,5 (2012)
A direct, one-pot and regioselective access to N-alkyl- and N-aryl-substituted 2-pyridones is described from readily available β-keto amides and either primary or secondary propargylic alcohols. This approach involves the combination of two different cooperative homogeneous and heterogeneous catalytic systems based on a transition metal oxide and a supported organocatalyst, respectively. Copyright
