1416448-66-2

Basic information

• Product Name: 10-(2-chlorophenyl)benzo[h]quinoline
• Synonyms: 10-(2-chlorophenyl)benzo[h]quinoline
• CAS NO: 1416448-66-2
• Molecular Weight: 289.764
• Mol File: 1416448-66-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 10-(2-chlorophenyl)benzo[h]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 10-(2-chlorophenyl)benzo[h]quinoline(1416448-66-2)
• EPA Substance Registry System: 10-(2-chlorophenyl)benzo[h]quinoline(1416448-66-2)

Safety Data

• Hazardous Substances Data: 1416448-66-2(Hazardous Substances Data)

Upstream product

• 230-27-3 7,8-benzoquinoline 
• 615-41-8 2-iodochlorobenzene 
• 408328-57-4 10-chlorobenzo[h]nquinoline 
• 3900-89-8 2-Chlorobenzeneboronic acid 

Relevant articles and documents

Expeditious and Solvent-Free Nickel-Catalyzed C?H Arylation of Arenes and Indoles

An efficient solvent-free nickel-catalyzed method for C?H bond arylation of arenes and indoles has been developed, which proceeds expeditiously through chelation assistance. The reaction is highly selective for mono-arylation and tolerates sensitive and structurally diverse functionalities, such as halides, ethers, amines, indole, pyrrole and carbazole. This reaction represents the first example of a nickel-catalyzed C?H arylation by monochelate assistance and symbolizes a rare precedent in solvent-free C?H arylation. Mechanistic investigations by various controlled reactions, kinetic studies, and deuterium labeling experiments suggest that the arylation follows a single electron transfer (SET) pathway involving the turnover-limiting C?H nickelation process.