1416449-89-2Relevant academic research and scientific papers
Asymmetric chiral ligand-directed alkene dioxygenation
Neufeldt, Sharon R.,Sanford, Melanie S.
, p. 46 - 49 (2013/04/10)
A Pd-catalyzed asymmetric alkene 1,2-dioxygenation reaction is described. The diastereoselectivity of the reaction is controlled by tethering a chiral oxime ether directing group to the alkene substrate. The best selectivities are obtained with 8-substituted menthone-derived oxime ether auxiliaries.
