141645-11-6

Basic information

• Product Name: Methanone, (4-methoxyphenyl)(3-methyl-5-nitro-2-benzofuranyl)-
• CAS NO: 141645-11-6
• Molecular Formula: C17H13NO5
• Molecular Weight: 311.294
• Mol File: 141645-11-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methanone, (4-methoxyphenyl)(3-methyl-5-nitro-2-benzofuranyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methoxyphenyl)(3-methyl-5-nitro-2-benzofuranyl)-(141645-11-6)
• EPA Substance Registry System: Methanone, (4-methoxyphenyl)(3-methyl-5-nitro-2-benzofuranyl)-(141645-11-6)

Safety Data

• Hazardous Substances Data: 141645-11-6(Hazardous Substances Data)

Upstream product

• 1450-76-6 1-(2-hydroxy-5-nitrophenyl)ethanone 
• 2196-99-8 2-chloro-1-(4-methoxyphenyl)ethanone 

Relevant articles and documents

An easy access to benzofurans via DBU induced condensation reaction of active 2-hydroxy acetophenones with phenacyl chlorides: A novel class of antioxidant agents

A convenient and efficient one-pot synthesis of benzofurans 3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j, 3k, 3l, 3m, 3n, 3o, 3p, 3q, 3r, 3s, 3t has been described from 2-hydroxy acetophenones and phenacyl chlorides in the presence of DBU. The procedure was applicable for a variety of phenacyl chlorides and provides a variety of benzofurans with higher yields. DBU acts as a base and as well as nucleophiles. All the derivatives were subjected to in vitro antioxidant screenings against representative 2,2'-diphenyl-1-picryl-hydrazyl and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radicals and results worth for further investigations.