1416618-81-9Relevant academic research and scientific papers
Direct one-pot cobalt(II) phthalocyanine catalyzed synthesis of N-substituted isoindolinones
Kumar, Vishal,Sharma, Upendra,Singh, Bikram,Kumar, Neeraj
, p. 1594 - 1598 (2013/02/25)
A direct one-pot synthetic approach is described wherein cobalt(II) phthalocyanine (CoPc) catalyzed reductive amination of 2-carboxybenzaldehyde, followed by intramolecular amidation afforded N-substituted isoindolinones. The method used diphenylsilane as reducing agent in ethanol. High chemoselectivity with excellent yield was obtained in most of the studied substrates.
