1416715-96-2Relevant academic research and scientific papers
Copper-catalyzed arylation of alkenyl aziridines via three-component coupling reaction involving alkynes and benzyne
Berti, Francesco,Crotti, Paolo,Cassano, Giulio,Pineschi, Mauro
, p. 2463 - 2468,6 (2012/12/12)
Alkenyl aziridines can be successfully arylated in a three-component coupling triggered by in situ generated benzyne with a simple copper catalyst (CuI-PPh, without the need of any palladium salts. The corresponding allylic amines can be obtained with good to high regioselectivity in mild reaction conditions with a variety of cyclic and acyclic alkenyl aziridines. A new domino reaction with ethyl propiolate to give tetrahydrophenanthridine was also found.
Copper-catalyzed arylation of alkenyl aziridines via three-component coupling reaction involving alkynes and benzyne
Berti, Francesco,Crotti, Paolo,Cassano, Giulio,Pineschi, Mauro
, p. 2463 - 2468 (2013/01/13)
Alkenyl aziridines can be successfully arylated in a three-component coupling triggered by in situ generated benzyne with a simple copper catalyst (CuI-PPh, without the need of any palladium salts. The corresponding allylic amines can be obtained with good to high regioselectivity in mild reaction conditions with a variety of cyclic and acyclic alkenyl aziridines. A new domino reaction with ethyl propiolate to give tetrahydrophenanthridine was also found. Georg Thieme Verlag Stuttgart. New York.
