141685-99-6

Basic information

• Product Name: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-[(4-methylphenyl)methyl]-
• CAS NO: 141685-99-6
• Molecular Formula: C14H19N
• Molecular Weight: 201.312
• Mol File: 141685-99-6.mol

Chemical Properties

• CAS DataBase Reference: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-[(4-methylphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-[(4-methylphenyl)methyl]-(141685-99-6)
• EPA Substance Registry System: Pyridine, 1,2,3,6-tetrahydro-1-methyl-4-[(4-methylphenyl)methyl]-(141685-99-6)

Safety Data

• Hazardous Substances Data: 141685-99-6(Hazardous Substances Data)

Upstream product

• 36995-48-9 4-[(bis-4-methylphenyl)methyl]pyridine 
• 74-88-4 methyl iodide 
• 872-85-5 pyridine-4-carbaldehyde 
• 106-38-7 para-bromotoluene 
• 33974-28-6 α-(4-methylphenyl)-4-pyridinemethanol 

Relevant articles and documents

Flexible N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogues: Synthesis and monoamine oxidase catalyzed bioactivation

Eighteen analogues of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were synthesized and evaluated as substrates of monoamine oxidase. In general, the flexible analogues, characterized by the presence of a methylene (or ethylene) bridge between the aryl/heteroaryl and tetrahydropyridyl moieties, were better substrates of the enzyme than the conformationally restricted MPTP. It is suggested that the increased oxidative activity of these flexible analogues reflects enhanced binding due to the ability of the C-4-aryl/heteroaryl substituent to gain access to a hydrophobic pocket within the substrate binding site.