1416892-63-1

Basic information

• Product Name: (R)-2-(4-(tert-butyl)phenyl)-1,2,3,4-tetrahydroquinoline
• Synonyms: (R)-2-(4-(tert-butyl)phenyl)-1,2,3,4-tetrahydroquinoline
• CAS NO: 1416892-63-1
• Molecular Weight: 265.398
• Mol File: 1416892-63-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (R)-2-(4-(tert-butyl)phenyl)-1,2,3,4-tetrahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(4-(tert-butyl)phenyl)-1,2,3,4-tetrahydroquinoline(1416892-63-1)
• EPA Substance Registry System: (R)-2-(4-(tert-butyl)phenyl)-1,2,3,4-tetrahydroquinoline(1416892-63-1)

Safety Data

• Hazardous Substances Data: 1416892-63-1(Hazardous Substances Data)

Upstream product

• 2005-43-8 2-bromoquinoline 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 917114-13-7 2-(4-(tert-butyl)phenyl)quinoline 
• 612-62-4 2-Chloroquinoline 
• 772-38-3 4-tert-Butylphenylacetylene 
• 529-23-7 o-aminobenzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 
• 943-27-1 4'-t-butylacetophenone 

Relevant articles and documents

Enantioselective Synthesis of Tetrahydroquinolines via One-Pot Cascade Biomimetic Reduction?

A novel and efficient protocol for the synthesis of chiral tetrahydroquinoline derivatives with excellent enantioselectivities and high yields has been developed through one-pot cascade biomimetic reduction. The detailed reaction pathway includes the acid-catalyzed and ruthenium-catalyzed formation of aromatic quinoline intermediates and biomimetic asymmetric reduction.

Cooperative Organocatalysis: A Systematic Investigation of Covalently Linked Organophosphoric Acids for the Stereoselective Transfer Hydrogenation of Quinolines

A series of covalently linked bis- and trisphosphoric acids was investigated for their application in the stereoselective transfer-hydrogenation of quinolines. In a combined experimental and theoretical study, it was found that the number and relative pos

Highly enantioselective spinol-derived phosphoric acid catalyzed transfer hydrogenation of diverse C=N-containing heterocycles

A highly efficient and enantioselective hydrogenation of diversely substituted C=N-containing heterocyclic compounds such as 3-aryl-1,4-benzoxazines and 2-arylquinolines was experimentally explored by using 1,1′-spirobiindane-7,7′-diol-derived chiral phosphoric acids as the catalyst. This method provides straightforward access to the corresponding tetrahydroquinolines and dihydro-2H-1,4-benzothiazines in high yields (85-99%) with excellent enantioselectivities (91-99%). The attractive features of this procedure, which include mild reaction conditions, operational simplicity, relatively low catalyst loading (1 mol-%), and high levels of enantioselectivities, make it a useful approach for the practical synthesis of optically active nitrogen-containing aromatic heterocycles.