1416892-65-3

Basic information

• Product Name: (R)-N,N-dimethyl-4-(1,2,3,4-tetrahydroquinolin-2-yl)aniline
• CAS NO: 1416892-65-3
• Molecular Weight: 252.359
• Mol File: 1416892-65-3.mol

Chemical Properties

• CAS DataBase Reference: (R)-N,N-dimethyl-4-(1,2,3,4-tetrahydroquinolin-2-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N,N-dimethyl-4-(1,2,3,4-tetrahydroquinolin-2-yl)aniline(1416892-65-3)
• EPA Substance Registry System: (R)-N,N-dimethyl-4-(1,2,3,4-tetrahydroquinolin-2-yl)aniline(1416892-65-3)

Safety Data

• Hazardous Substances Data: 1416892-65-3(Hazardous Substances Data)

Upstream product

• 16032-41-0 2-(4-(dimethylamino)phenyl)quinoline 
• 529-23-7 o-aminobenzaldehyde 
• 17573-94-3 4-ethynyl-N,N-dimethylaniline 

Relevant articles and documents

Spiro-Bicyclic Bisborane Catalysts for Metal-Free Chemoselective and Enantioselective Hydrogenation of Quinolines

A new series of spiro-bicyclic bisborane catalysts has been prepared by means of hydroboration reactions of C2-symmetric spiro-bicyclic dienes with HB(C6F5)2 and HB(p-C6F4H)2. When used for hydrogenation of quinolines, these catalysts give excellent yields and enantiomeric excesses, and show turnover numbers of up to 460. The most attractive feature of these metal-free hydrogenation reactions was the broad functional-group tolerance, making this method complementary to existing methods for quinoline hydrogenation.

Enantioselective cooperative triple catalysis: Unique roles of Au(i)/amine/chiral Bronsted acid catalysts in the addition/ cycloisomerization/transfer hydrogenation cascade

An enantioselective cooperative process involving the concerted/ simultaneous action of three different catalysts i.e. Au(i)/amine/chiral Bronsted acid catalysts has been realized for the synthesis of 2-substituted tetrahydroquinolines from 2-aminobenzaldehydes and terminal alkynes.