1416907-26-0Relevant articles and documents
Synthesis of cyclopentanyl carbocyclic 5-fluorocytosine ((-)-5-fluorocarbodine) using a facially selective hydrogenation approach
Cho, Jong Hyun,Amblard, Franck,Coats, Steven J.,Schinazi, Raymond F.
, p. 723 - 727 (2013)
An efficient synthetic route to biologically relevant (-)-5-fluorocarbodine 6 was developed. Direct coupling of N6-protected 5-fluorouracil 15 with cyclopentenyl intermediate 13, followed by formation of a macrocycle between the base and the ca