1416910-09-2

Basic information

• Product Name: (S)-1-(4-chloro-phenyl)-2-{4-[(R)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-1-hydroxy-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one
• Synonyms: (S)-1-(4-chloro-phenyl)-2-{4-[(R)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-1-hydroxy-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one
• CAS NO: 1416910-09-2
• Molecular Weight: 598.16
• Mol File: 1416910-09-2.mol

Chemical Properties

• CAS DataBase Reference: (S)-1-(4-chloro-phenyl)-2-{4-[(R)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-1-hydroxy-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-chloro-phenyl)-2-{4-[(R)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-1-hydroxy-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one(1416910-09-2)
• EPA Substance Registry System: (S)-1-(4-chloro-phenyl)-2-{4-[(R)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-1-hydroxy-ethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one(1416910-09-2)

Safety Data

• Hazardous Substances Data: 1416910-09-2(Hazardous Substances Data)

Upstream product

• 473254-30-7 4-acetyl-1λ6-thiane-1,1-dione 
• 1416910-07-0 (S)-1-(4-chloro-phenyl)-2-{4-[1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-1-hydroxyethyl]-phenyl}-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one 
• 1313365-55-7 (4-isopropoxy-5-methoxy-2-{[(E)-(S)-2-methyl-propane-2-sulfinylimino]-methyl}-phenyl)-acetic acid ethyl ester 
• 1313365-56-8 {2-[(S)-(4-chloro-phenyl)-((S)-2-methyl-propane-2-sulfinylamino)-methyl]-4-isopropoxy-5-methoxy-phenyl}-acetic acid ethyl ester 
• 1313365-57-9 (S)-1-(4-chloro-phenyl)-7-isopropoxy-6-methoxy-1,4-dihydro-2H-isoquinolin-3-one 
• 1416910-08-1 1-(4-bromo-phenyl)-1-(1,1-dioxo-hexahydro-1-thiopyran-4-yl)-ethanol 
• 1313365-54-6 (2-formyl-4-isopropoxy-5-methoxy-phenyl)-acetic acid ethyl ester 
• 1256581-66-4 (4-isopropoxy-3-methoxy-phenyl)-acetic acid ethyl ester 
• 60563-13-5 ethyl homovanillate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 4526-07-2 1,4-bis(trimethylsilyl)-1,3-butadiyne 
• 589-87-7 1,4-bromoiodobenzene 
• 14064-15-4 (4-chlorophenyl)trimethylstannane 

Relevant articles and documents

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HYDROXY SUBSTITUTED ISOQUINOLINONE DERIVATIVES

The invention relates to compounds of formula (I): as defined in the application. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.