1416983-00-0Relevant articles and documents
Catalytic nazarov reaction of aryl vinyl ketones via binary acid strategy
Xi, Zhi-Guo,Zhu, Lihui,Luo, Sanzhong,Cheng, Jin-Pei
, p. 606 - 613 (2013)
We describe herein a viable binary acid strategy for the catalytic Nazarov reaction of aryl vinyl ketones. Simply combining a Lewis acid and a Bronsted acid led to a dramatic enhancement of the catalytic activity in the Nazarov reaction of aryl vinyl β-ketoesters. The obtained optimal binary acid catalyst In(OTf)3/diphenyl phosphoric acid (DPP) can be applied to a range of aryl vinyl ketones with good activity. A trend of reactivity has also been summarized on the basis of mapping of the substituents.