1417159-94-4

Basic information

• Product Name: N-(buta-2,3-dien-1-yl)-4-nitrobenzamide
• CAS NO: 1417159-94-4
• Molecular Weight: 218.212
• Mol File: 1417159-94-4.mol

Chemical Properties

• CAS DataBase Reference: N-(buta-2,3-dien-1-yl)-4-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(buta-2,3-dien-1-yl)-4-nitrobenzamide(1417159-94-4)
• EPA Substance Registry System: N-(buta-2,3-dien-1-yl)-4-nitrobenzamide(1417159-94-4)

Safety Data

• Hazardous Substances Data: 1417159-94-4(Hazardous Substances Data)

Relevant articles and documents

Solid-phase synthesis of N-(buta-2,3-dien-1-yl)amides by the Crabbé reaction

The Crabbé homologation of polymer-supported propargylamine with paraformaldehyde, CuI, and dicyclohexylamine in 1,4-dioxane at 100 C, followed by cleavage with dilute trifluoroacetic acid, furnishes N-(buta-2,3-dien-1-yl) amides as isolable products. The N-acyltriazene linker on Merrifield resin serves simultaneously as a protecting group for the nucleophilic primary amine. The product diversity is achieved by altering the acyl chloride in the acylation of the triazene linker. In addition to being a new route to nitrogen-containing allenes, our solid-phase method enables immobilization of these reactive cumulated dienes for further synthetic operations.