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141732-76-5 Usage


Exenatide acetate is a 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum). It differs from exendin-3 only in two positions close to the N-terminus and is a white solid. As an incretin mimetic, exenatide acetate acts as an agonist of the glucagon-like peptide-1 (GLP-1) receptor, similar to GLP-1 but with prolonged activity. It increases the postprandial production of insulin and suppresses the secretion of glucagon.


Used in Pharmaceutical Industry:
Exenatide acetate is used as a medication for the treatment of type II diabetes. As an incretin mimetic, it acts as an agonist of the GLP-1 receptor, increasing acinar cAMP without stimulating amylase release. This leads to an augmentation of postprandial insulin production and suppression of glucagon secretion, making it a valuable treatment option for managing blood sugar levels in patients with type II diabetes.

Clinical Use

39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.

Drug interactions

Potentially hazardous interactions with other drugs Anticoagulants: possibly enhances anticoagulant effect of warfarin. Other nephrotoxins: avoid concomitant use.


Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.

Check Digit Verification of cas no

The CAS Registry Mumber 141732-76-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,7,3 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 141732-76:
115 % 10 = 5
So 141732-76-5 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017


1.1 GHS Product identifier

Product name Exenatide Acetate

1.2 Other means of identification

Product number -
Other names Exenatide acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141732-76-5 SDS

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