1417411-71-2

Basic information

• Product Name: C₁₆H₁₁BrClN₅O₃
• Synonyms: C₁₆H₁₁BrClN₅O₃
• CAS NO: 1417411-71-2
• Molecular Weight: 436.652
• Mol File: 1417411-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₁BrClN₅O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₁BrClN₅O₃(1417411-71-2)
• EPA Substance Registry System: C₁₆H₁₁BrClN₅O₃(1417411-71-2)

Safety Data

• Hazardous Substances Data: 1417411-71-2(Hazardous Substances Data)

Upstream product

• 1392413-56-7 6-bromo-3-chloro-2-methylquinoxaline 
• 1417411-63-2 (7-bromo-3-methylquinoxalin-2-yl)hydrazine 
• 5344-49-0 2-chloro-6-nitrobenzoic acid 
• 65407-77-4 (6-bromo-3-methylquinoxalin-2-yl)hydrazine 

Downstream Products

• 1417411-73-4 8-bromo-1-(2-chloro-6-fluorophenyl)-4-methyl[1,2,4]triazolo[4,3-a]quinoxaline 
• 1417411-74-5 8-bromo-1-(2-chloro-6-fluorophenyl)-4-methyl[1,2,4]triazolo[4,3-a]quinoxaline 

Relevant articles and documents

1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES

The present invention relates to novel l-aryl-4-methyl-[l,2,4]triazolo[4,3-a]- quinoxaline derivatives as inhibitors of phosphodiesterase 2 (PDE2) and to a lesser extent of phosphodiesterase 10 (PDE10) or as inhibitors of both, phosphodiesterases 2 and 10. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which PDE2 is involved, or disorders in which both PDE2 and PDE10 are involved, such as neurological and psychiatric disorders, and endocrinological or metabolic diseases. The present invention also relates to radiolabeled compounds which may be useful for imaging and quantifying the PDE2 enzyme in tissues, using positron- emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a host, in vitro or in vivo and to precursors of said compounds.