141747-97-9

Upstream product

• 53545-96-3 6-bromo-2,2-dimethylhexanenitrile 

Downstream Products

• 206263-26-5 2-[[[5-[[2,2-dimethyl-6-[(4-(3,4-methylenedioxyphenyl)-6-phenyl-2-pyridinyl)oxy]-1-hexanamino]carbonyl]-2-pyridinyl]hydrazono]methyl]-benzenesulfonic Acid 
• 206267-60-9 3-((N-(6-(4-benzo[d]1,3-dioxolan-5-yl-6-phenyl (2-pyridyloxy))-2,2-dimethylhexyl)carbamoyl) amino)-benzoic acid 
• 206266-50-4 1-Amino-2,2-dimethyl-6-[(4-(3,4-methylenedioxyphenyl)-6-phenyl-2-pyridinyl)oxy]-hexane 

Relevant academic research and scientific papers

Radiopharmaceuticals for imaging infection and inflammation

The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and

LTB4 antagonists and radiopharmaceuticals for imaging infection and inflammation

The present invention provides novel radiopharmaceutials useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and methods of diagnosing diseases associated with infection or inflammation in patients in need of such diagnosis. The radiopharmaceuticals bind in vivo to the leukotriene B4 (LTB4) receptor on the surface of leukocytes which accumulate at the site of infection and inflammation. The reagents provided by this invention are also useful for the treatment of diseases associated with infection and inflammation.

Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation

The present invention provides novel diagnostic compositions comprising a radiolabeled LTB4 binding agent and a radiolabeled perfusion imaging agent, diagnostic kits comprising such compositions, and methods of concurrent imaging in a mammal comprising ad

Radiopharmaceuticals for imaging infection and inflammation

The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and

SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS

This invention relates to compounds having selective LTB 4 antagonist properties, compositions comprising said compounds and methods for the treatment of disorders involving LTB 4 agonist-mediated activity utilizing said compositions wherein the compounds