1417540-41-0Relevant academic research and scientific papers
Bioactive pregnane-type steroids from the soft coral Scleronephthya gracillimum
Fang, Hui-Yu,Liaw, Chih-Chuang,Chao, Chih-Hua,Wen, Zhi-Hong,Wu, Yang-Chang,Hsu, Chi-Hsin,Dai, Chang-Feng,Sheu, Jyh-Horng
, p. 9694 - 9700 (2012)
Nine new steroids, sclerosteroids A-I (1, 5, 6, 8-13), along with 18 known metabolites (2-4, 7, 14-27), were isolated from the soft coral Scleronephthya gracillimum. These structures were elucidated on the basis of detailed spectroscopic analysis. The absolute configurations of sugar moieties in steroidal glycosides 10-13 were determined by HPLC analysis of the o-tolylthiocarbamate derivatives of the liberated sugars from hydrolysis of these steroidal giycosides. Cytotoxic and anti-inflammatory activities of these compounds were measured in vitro.
Bioactive pregnane-type steroids from the soft coral Scleronephthya gracillimum
Fang, Hui-Yu,Liaw, Chih-Chuang,Chao, Chih-Hua,Wen, Zhi-Hong,Hsu, Chi-Hsin,Sheu, Jyh-Horng,Wu, Yang-Chang,Dai, Chang-Feng
, p. 9694 - 9700,7 (2012/12/11)
Nine new steroids, sclerosteroids A-I (1, 5, 6, 8-13), along with 18 known metabolites (2-4, 7, 14-27), were isolated from the soft coral Scleronephthya gracillimum. These structures were elucidated on the basis of detailed spectroscopic analysis. The absolute configurations of sugar moieties in steroidal glycosides 10-13 were determined by HPLC analysis of the o-tolylthiocarbamate derivatives of the liberated sugars from hydrolysis of these steroidal giycosides. Cytotoxic and anti-inflammatory activities of these compounds were measured in vitro.
