1417567-47-5

Basic information

• Product Name: 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine hydrochloride
• CAS NO: 1417567-47-5
• Molecular Weight: 197.667
• Mol File: 1417567-47-5.mol

Chemical Properties

• CAS DataBase Reference: 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine hydrochloride(1417567-47-5)
• EPA Substance Registry System: 2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-amine hydrochloride(1417567-47-5)

Safety Data

• Hazardous Substances Data: 1417567-47-5(Hazardous Substances Data)

Usage

Chemical class

Ethylamines

Structure

Pyrrolopyridine

Use

Building block for the synthesis of various organic compounds

Biological and therapeutic activities

Potential exists due to structure

Solubility

Increased in aqueous solutions due to hydrochloride salt form

Pharmaceutical drug development potential

Exists due to structural and chemical properties

Relevant articles and documents

Aza-Tryptamine Substrates in Monoterpene Indole Alkaloid Biosynthesis

Biosynthetic pathways can be hijacked to yield novel compounds by introduction of novel starting materials. Here we have altered tryptamine, which serves as the starting substrate for a variety of alkaloid biosynthetic pathways, by replacing the indole with one of four aza-indole isomers. We show that two aza-tryptamine substrates can be successfully incorporated into the products of the monoterpene indole alkaloid pathway in Catharanthus roseus. Use of unnatural heterocycles in precursor-directed biosynthesis, in both microbial and plant natural product pathways, has not been widely demonstrated, and successful incorporation of starting substrate analogs containing the aza-indole functionality has not been previously reported. This work serves as a starting point to explore fermentation of aza-alkaloids from other tryptophan- and tryptamine-derived natural product pathways.