1417609-72-3Relevant academic research and scientific papers
Convergent solid-phase synthesis of N-glycopeptides facilitated by pseudoprolines at consensus-sequence Ser/Thr residues
Ullmann, Vera,R?disch, Marisa,Boos, Irene,Freund, Jutta,P?hner, Claudia,Schwarzinger, Stefan,Unverzagt, Carlo
supporting information, p. 11566 - 11570 (2013/01/15)
Remote control: The formation of aspartimides is greatly decreased during peptide elongation and during convergent sugar couplings of Asp-X-Ser/Thr peptides that contain a pseudoproline (red; see scheme). The robust approach efficiently joins complex peptides and N-glycans on the solid phase thus facilitating the availability of glycopeptides and glycoproteins. Copyright
