141766-10-1Relevant articles and documents
Synthesis of artificial receptors as potential candidates for recognition and binding of pterin analogs
Papadopoulou,Goswami,Hamilton
, p. 675 - 681 (2007/10/02)
Open chain podands 2a-c and macrocycles 2d-e have been synthesized as potential candidates for 4-aminopterin recognition and binding, featuring H-bonding characteristics and 'stacking interaction' 2e. Preliminary binding studies between 6, 7, and 8 (simpler analogs of the above 2a-e) as 'hosts' and appropriate 'guests', showed that carbamates 2a and 2e are the most promising receptors for 4-aminopterin binding.