141772-31-8

Basic information

• Product Name: 5-AMino-2-chloro-4-fluoro-benzoic acid Methyl ester
• Synonyms: 5-AMino-2-chloro-4-fluoro-benzoic acid Methyl ester;Methyl 5-aMino-2-chloro-4-fluorobenzoate
• CAS NO: 141772-31-8
• Molecular Formula: C₈H₇ClFNO₂
• Molecular Weight: 203.5980832
• Mol File: 141772-31-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-AMino-2-chloro-4-fluoro-benzoic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMino-2-chloro-4-fluoro-benzoic acid Methyl ester(141772-31-8)
• EPA Substance Registry System: 5-AMino-2-chloro-4-fluoro-benzoic acid Methyl ester(141772-31-8)

Safety Data

• Hazardous Substances Data: 141772-31-8(Hazardous Substances Data)

Usage

Uses

Methyl 5-Amino-2-chloro-4-fluorobenzoate is an intermediate of Saflufenacil (S081800), a herbicide of the pyrimidinedione chemical class used for the preplant burndown and selective preemergence dicot weed control in different field crops.

Upstream product

• 114776-15-7 2-chloro-4-fluoro-5-nitrobenzoic acid 
• 85953-30-6 methyl 2-chloro-4-fluoro-5-nitrobenzoate 

Downstream Products

• 374718-19-1 2-fluoro-4-chloro-5-methoxycarbonylphenyl isocyanate 
• 160415-92-9 2-Chloro-5-ethoxycarbonylamino-4-fluoro-benzoic acid methyl ester 

Relevant articles and documents

Design, synthesis, and molecular simulation studies of N-phenyltetrahydroquinazolinones as protoporphyrinogen IX oxidase inhibitors

Discovering new protoporphyrinogen oxidase (PPO, EC 1.3.3.4) inhibitors is a promising direction for agrochemical research. Herein, we reported the discovery and in silico structure-guided optimization of N-phenyltetrahydroquinazolinones 1 and 2 as new PP

A novel synthesis of 4H-1,4-benzoxazines

The reaction of methyl 2-chloro-5-ethoxycarbonylamino-4-fluorobenzoate (4a) and 1-bromo-3,3-dimethyl-2-butanone (2) in the presence of 2.2 eq of lithium bis(trimethylsilyl)amide afforded the 4H-1,4-benzoxazine (6a) in good yield instead of the expected 4-