1417743-49-7

Basic information

• Product Name: 1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)-
• Synonyms: 1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)-;(R)-1-(tert-butoxycarbonyl)-4,4-dimethylpyrrolidine-2-carboxylic acid;(R)-1-Boc-4,4-dimethyl-pyrrolidine-2-carboxylic acid
• CAS NO: 1417743-49-7
• Molecular Formula: C12H21NO4
• Molecular Weight: 243.29944
• EINECS: -0
• Mol File: 1417743-49-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)-(1417743-49-7)
• EPA Substance Registry System: 1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)-(1417743-49-7)

Safety Data

• Hazardous Substances Data: 1417743-49-7(Hazardous Substances Data)

Usage

General Description

1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)- is a chemical compound with the molecular formula C12H23NO4. It is a derivative of pyrrolidine and is commonly referred to as the (2R)-Tert-butyl 4,4-dimethyl-2-pyrrolidinecarboxylate. 1,2-Pyrrolidinedicarboxylic acid, 4,4-diMethyl-, 1-(1,1-diMethylethyl) ester, (2R)- is a chiral molecule, meaning it has an asymmetrical carbon atom and exists in two enantiomeric forms. It is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and agrochemicals. Additionally, it has potential applications in the field of medicine, particularly in the development of new drugs for the treatment of various diseases.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1417743-48-6 (R)-2-benzyl 1-tert-butyl 4,4-dimethylpyrrolidine-1,2-dicarboxylate 
• 1417743-47-5 (R)-2-benzyl 1-tert-butyl 4,4-dimethyl-5-oxopyrrolidine-1,2-dicarboxylate 
• 1417743-46-4 (R)-1-(tert-butoxycarbonyl)-4,4-dimethyl-5-oxopyrrolidine-2-carboxylic acid 
• 1417743-45-3 (R)-tert-butyl 2-(hydroxymethyl)-4,4-dimethylpyrrolidine-1-carboxylate 
• 493035-98-6 (R)-5-(hydroxymethyl)-3,3-dimethylpyrrolidin-2-one 
• 1417743-44-2 (R)-3,3,6,6-tetramethyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-one 
• 66673-40-3 (R)-5-hydroxymethylpyrrolidin-2-one 

Downstream Products

• 1417743-75-9 (R)-tert-butyl 2-((1-(4-(methoxycarbonyl)phenyl)cyclopropyl)carbamoyl)-4,4-dimethylpyrrolidine-1-carboxylate 

Relevant articles and documents

CYCLIC AMINE DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS

There is described a novel group of cyclic amine derivative compounds, having an EP4 receptor antagonistic activity and specifically pharmaceutical compounds which are useful for the treatment or alleviation of Prostaglandin E mediated diseases. The present invention therefore relates to novel compounds which are selective antagonists of the EP4 subtype of PGE2 receptors with analgesic and antinflammatory activity, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments, inter alia for the treatment or alleviation of Prostaglandin E mediated diseases such as acute and chronic pain, osteoarthritis, inflammation-associated disorder as arthritis, rheumatoid arthritis, cancer, migraine and endometriosis.