1417797-64-8

Basic information

• Product Name: 5-amino-7-(4-hydroxyphenyl)-1,7-dihydropyrano [3,2-b]pyrrole-6-carbonitrile
• Synonyms: 5-amino-7-(4-hydroxyphenyl)-1,7-dihydropyrano [3,2-b]pyrrole-6-carbonitrile
• CAS NO: 1417797-64-8
• Molecular Weight: 253.26
• Mol File: 1417797-64-8.mol

Chemical Properties

• CAS DataBase Reference: 5-amino-7-(4-hydroxyphenyl)-1,7-dihydropyrano [3,2-b]pyrrole-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-7-(4-hydroxyphenyl)-1,7-dihydropyrano [3,2-b]pyrrole-6-carbonitrile(1417797-64-8)
• EPA Substance Registry System: 5-amino-7-(4-hydroxyphenyl)-1,7-dihydropyrano [3,2-b]pyrrole-6-carbonitrile(1417797-64-8)

Safety Data

• Hazardous Substances Data: 1417797-64-8(Hazardous Substances Data)

Upstream product

• 29212-57-5 3-hydroxy-1H-pyrrole 
• 123-08-0 4-hydroxy-benzaldehyde 
• 109-77-3 malononitrile 

Relevant articles and documents

Synthesis and in vitro antimicrobial evaluation of 5-amino-7-aryl-6-cyano- 4H-pyrano[3,2,b]pyrrole derivatives catalyzed by reusable ZrOCl 2·8H2O

An efficient synthesis of a new series of 5-amino-7-aryl-6-cyano-4H- pyrano[3,2-b]pyrrole derivatives from the reaction of 3-hydroxypyrrole, malononitrile, and various aromatic aldehydes using ZrOCl2· 8H2O, an environmentally friendly catalyst under a thermal solvent-free green procedure is described. This simple protocol offer advantages such as shorter reaction times, simple work-up and excellent yield. The catalyst ZrOCl2·8H2O can be reused. The reusability of the catalyst has been studied for the synthesis of 5-amino-7-aryl-6-cyano- 4H-pyrano[3,2-b]pyrrole. All the compounds were screened for their antibacterial and antifungal activity.

A novel multicomponent Zr-catalyzed synthesis of functionalized pyrano[3,2-b]pyrrole derivatives

A novel, efficient, and rapid procedure, one-pot condensation of 3-hydroxypyrrole, malononitrile, and aromatic aldehydes, with 10 mol % bis[N-(3,5-dicumylsalicylidene)anthracylaminato]zirconium(IV) dichloride as catalyst, in the presence of ultrasonic irradiation, has been developed for synthesis of 5-amino-7-aryl-6-cyano-4H-pyrano[3,2-b]pyrrole derivatives.