1417797-65-9Relevant academic research and scientific papers
Synthesis and in vitro antimicrobial evaluation of 5-amino-7-aryl-6-cyano- 4H-pyrano[3,2,b]pyrrole derivatives catalyzed by reusable ZrOCl 2·8H2O
Hussain, A. Mohammed,Mansoor, S. Sheik,Aswin,Logaiya,Sudhan
, p. 91 - 100 (2014/03/21)
An efficient synthesis of a new series of 5-amino-7-aryl-6-cyano-4H- pyrano[3,2-b]pyrrole derivatives from the reaction of 3-hydroxypyrrole, malononitrile, and various aromatic aldehydes using ZrOCl2· 8H2O, an environmentally friendly catalyst under a thermal solvent-free green procedure is described. This simple protocol offer advantages such as shorter reaction times, simple work-up and excellent yield. The catalyst ZrOCl2·8H2O can be reused. The reusability of the catalyst has been studied for the synthesis of 5-amino-7-aryl-6-cyano- 4H-pyrano[3,2-b]pyrrole. All the compounds were screened for their antibacterial and antifungal activity.
A novel multicomponent Zr-catalyzed synthesis of functionalized pyrano[3,2-b]pyrrole derivatives
Damavandi, Saman,Sandaroos, Reza,Zohuri, Gholam Hossein,Ahmadjo, Saied
, p. 307 - 315 (2014/02/14)
A novel, efficient, and rapid procedure, one-pot condensation of 3-hydroxypyrrole, malononitrile, and aromatic aldehydes, with 10 mol % bis[N-(3,5-dicumylsalicylidene)anthracylaminato]zirconium(IV) dichloride as catalyst, in the presence of ultrasonic irradiation, has been developed for synthesis of 5-amino-7-aryl-6-cyano-4H-pyrano[3,2-b]pyrrole derivatives.
