1417818-96-2

Upstream product

• 1019-85-8 2-(4-chlorophenyl)benzimidazole 
• 20718-17-6 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-phenylethan-1-one 
• 1281983-07-0 2-(2-bromo-4-chloro-phenyl)-1H-benzoimidazole 
• 120-46-7 1,3-diphenylpropanedione 
• 2562-81-4 2-(naphthalen-1-yl)-1H-benzo[d]imidazole 
• 932-87-6 1-Bromo-2-phenylacetylene 

Relevant academic research and scientific papers

Rhodium-Catalyzed Annulation of 2-Arylimidazoles and α-Aroyl Sulfoxonium Ylides toward 5-Arylimidazo[2,1- a ]isoquinolines

A Rh-catalyzed annulation between 2-aryl-1 -benzo[ d ]imidazoles and α-aroyl sulfoxonium ylides was developed, affording a series of benzimidazo[2,1- a ]isoquinolines in moderate to excellent yields. This procedure proceeded with the sequential ortho C-H functionalization and cyclization, representing a facile and straightforward pathway to access such frameworks.

An efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a] isoquinolines via sequential α-arylation of carbonyl and deacylation catalyzed by CuI

Dibenzoyl methane was found to undergo α-arylation of carbonyl and deacylation reaction with 2-(2-bromophenyl)-1H-benzo[d]imidazoles catalyzed by CuI in the presence of Cs2CO3, and provided an efficient synthesis of 6-arylbenzo[4,5]i

Nucleophilic addition of benzimidazoles to alkynyl bromides/palladium- catalyzed intramolecular C-H vinylation: Synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines

An efficient "one-pot" route for the synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C-H vinylation.