1417819-40-9Relevant academic research and scientific papers
Regio- and stereoselective synthesis of 1-(1-halovinyl)-1H-indoles from 1-ethynyl-1H-indoles with in situ generated HX
Sato, Akihiro H.,Ohashi, Kazuhiro,Ito, Kouhei,Iwasawa, Tetsuo
, p. 2878 - 2881 (2013/06/26)
A facile approach to 1-(1-halovinyl)-1H-indoles from readily accessible 1-ethynyl-1H-indoles with in situ generated HX is described. The simple protocol enables a regio- and stereoselective hydrohalogenation to the triple bonds in gram-scale, and provides a general entry for novel N-alkenylindole derivatives.
Nucleophilic addition of benzimidazoles to alkynyl bromides/palladium- catalyzed intramolecular C-H vinylation: Synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines
Peng, Jinsong,Shang, Guoning,Chen, Chunxia,Miao, Zhongshuo,Li, Bin
, p. 1242 - 1248 (2013/04/10)
An efficient "one-pot" route for the synthesis of benzo[4,5]imidazo[2,1-a] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C-H vinylation.
