1417819-45-4Relevant academic research and scientific papers
A serendipitous conversion of enaminolactone nitriles with primary amines: A new synthesis of substituted 2-aminopyridine derivatives
Cheikh, Nawel,Villemin, Didier,Bar, Nathalie,Lohier, Jean-Fran?ois,Choukchou-Braham, Nourredine,Mostefa-Kara, Bachir,Sopkova, Jana
, p. 1234 - 1247 (2013)
In the course of our studies on Cerpegin analogues synthesis, a serendipitous reactivity of enaminolactone nitrile has been observed. Instead of expecting iminocerpegins, we have gained new class of substituted 2-aminopyridines. The methodology has been applied on a wide range of primary amines, as aliphatic, aromatic, heteroaromatic and also, diamines, hydrazines and chiral amines.
