1418003-75-4Relevant academic research and scientific papers
A doubly axially chiral phosphoric acid catalyst for the asymmetric tandem oxyfluorination of enamides
Honjo, Takashi,Phipps, Robert J.,Rauniyar, Vivek,Toste, F. Dean
, p. 9684 - 9688 (2012/10/30)
Double agent: Enantioselective tandem oxyfluorination of enamides using a doubly axially chiral phosphoric acid catalyst is reported. The chiral phosphoric acid catalyst controls both a fluorination step, using a chiral anion phase-transfer strategy, and addition to the resulting imine under the guise of Br?nsted acid catalysis. Copyright
