141803-60-3Relevant academic research and scientific papers
Synthesis, antimicrobial and antiviral activities of novel polyphenolic compounds
Parmar,Bisht,Jain, Rajni,Singh, Suddham,Sharma,Gupta, Suman,Malhotra, Sanjay,Tyagi,Vardhan, Anand,Pati,Vanden Berghe,Vlietinck
, p. 220 - 232 (2007/10/03)
Natural and synthetic phenolic compounds belonging to the classes of flavones, coumarins, xanthones, chalcones. isotlavones and desoxybenzoins have been prepared or isolated from plant species, characterized and tested against a battery of 10 pathogenic bacteria, 1 yeast, 3 fungi and 3 viruses. Only two of the compounds show some moderate bacteriostatic activity against gram-positive cocci, but are like all other products inactive against gram-negative bacteria, yeasts and fungi. On the contrary, two flavones, one desoxybenzoin and one diacetoxycoumarin exhibited pronounced antiviral properties against some of the viruses tested. Five other coumarin analogs possessed moderate anti-poliomyelitis properties and one xanthone is to a lesser extent active against Vesicular stomatitis virus. Of the compounds synthesized nine are new compounds.
