1418035-91-2Relevant academic research and scientific papers
Gold-catalyzed cyclization of enediynes and arenediynes to 6H-benzo[c]chromen-6-one and dibenzo[c,h]chromen-6-one derivatives
Chen, Chin-Chau,Hsu, Chia-Ling,Wu, Ming-Jung
, p. 1034 - 1043 (2019/01/26)
The efficient synthesis of 6H-benzo[c]chromen-6-one and dibenzo[c,h]chromen-6-one derivatives is described. Thus, treatment of arenediynes 1 and enediynes 5 with 5 mol % Ph3PAuCl and 10 mol % of AgSbF6 in refluxing toluene gave dibenzo[c,h]chromen-6-ones 4 and 6H-benzo[c]chromen-6-ones 6, in good yields, respectively.
CO extrusion in homogeneous gold catalysis: Reactivity of gold acyl species generated through water addition to gold vinylidenes
Bucher, Janina,St?sser, Tim,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
, p. 1666 - 1670 (2015/01/30)
Herein, we describe a new gold-catalyzed decarbonylative indene synthesis. Synergistic σ,π-activation of diyne substrates leads to gold vinylidene intermediates, which upon addition of water are transformed into gold acyl species, a type of organogold compound hitherto only scarcely reported. The latter are shown to undergo extrusion of CO, an elementary step completely unknown for homogeneous gold catalysis. By tuning the electronic and steric properties of the starting diyne systems, this new reactivity could be exploited for the synthesis of indene derivatives in high yields.
Assembly of fused indenes via Au(i)-catalyzed C1-C5 cyclization of enediynes bearing an internal nucleophile
Hou, Qiwen,Zhang, Zhenhua,Kong, Fanji,Wang, Shaozhong,Wang, Huaqin,Yao, Zhu-Jun
supporting information, p. 695 - 697 (2013/02/25)
A tandem reaction initiated by Au(i)-catalyzed C1-C5 cyclization of enediynes bearing an internal carboxy nucleophile has been developed, providing a distinctive methodology for the assembly of fused indenes including indeno[1,2-c]isochromen-5(11H)-ones and indeno[1,2-b]pyran-2(5H)-ones. A mechanism involving the concerted formation of the five- and six-membered rings was proposed.
