141806-46-4Relevant academic research and scientific papers
Stereochemistry of remote dianion addition to imines. Application to the synthesis of (1S, 8aS)-1-hydroxyindolizidine
Green, Diana L. C.,Kiddle, James J.,Thompson, Charles M.
, p. 2865 - 2874 (2007/10/02)
A stereoselective route to (1S, 8aS)-1-hydroxyindolizidine is reported herein that incorporates as a pivotal step the diastereoselective addition of the dianion of 4-(phenylsulfonyl)butanoic acid (4-PSBA) to a chiral α-benzyloxymethyl imine.
Synthesis of (-)-Slaframine and Related Indolizidines
Pearson, William H.,Bergmeier, Stephen C.,Williams, John P.
, p. 3977 - 3987 (2007/10/02)
An enantioselective synthesis of the indolizidine alkaloid (-)-slaframine 1 is reported.Reductive double cyclization of the azido epoxy tosylate 48 afforded the indolizidine 52, which was converted to (-)-slaframine in two steps.The cyclization substrate
