141807-38-7Relevant academic research and scientific papers
Ni(0)-Catalyzed Cross Coupling of Aryl O-Carbamates and Aryl Triflates with Grignard Reagents. Directed Ortho Metalation-Aligned Synthetic Methods for Polysubstituted Aromatics via a 1,2-Dipole Equivalent
Sengupta, Saumitra,Leite, Magda,Raslan, Delio Soares,Quesnelle, Claude,Snieckus, Victor
, p. 4066 - 4068 (2007/10/02)
The first Ni(0)-catalyzed cross-coupling reactions of aryl O-carbamates and aryl triflates with Grignard reagents (Scheme I) to give diversely polysubstituted aromatics 2d and 2e (Table I) which feature regiospecificity based on directed ortho metalation (carbamate), minimal β-hydride elimination (triflate), and dependence on steric and electronic effects are described.
