1418129-51-7

Basic information

• Product Name: 6-methyl-2-(4-tolylamino)cyclohex-2-en-1-one
• Synonyms: 6-methyl-2-(4-tolylamino)cyclohex-2-en-1-one
• CAS NO: 1418129-51-7
• Molecular Weight: 215.295
• Mol File: 1418129-51-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-methyl-2-(4-tolylamino)cyclohex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-(4-tolylamino)cyclohex-2-en-1-one(1418129-51-7)
• EPA Substance Registry System: 6-methyl-2-(4-tolylamino)cyclohex-2-en-1-one(1418129-51-7)

Safety Data

• Hazardous Substances Data: 1418129-51-7(Hazardous Substances Data)

Upstream product

• 3008-43-3 3-methylcyclohexane-1,2-dione 
• 106-49-0 p-toluidine 

Downstream Products

• 1418129-53-9 2-methoxy-3-methyl-N-(4-tolyl)aniline 

Relevant articles and documents

Synthetic approach for constructing the 1-oxygenated carbazole core and its application to the preparation of natural alkaloids

An efficient synthetic approach for the construction of the 1-oxygenated carbazole core is described. The condensation of cyclohexane-1,2-diones with a series of anilines yielded the corresponding 2-anilinocyclohex-2-en-1-ones, followed by the one-pot aromatization/methylation process of the latter to provide N-aryl-2-methoxyanilines. A palladium(II)-catalyzed cyclization of these N-aryl-2-methoxyanilines afforded the desired 1-methoxycarbazole frame in high overall yields. This protocol was implemented for the total synthesis of the naturally occurring glycozolicine and 6-methoxymurrayanine.