1418136-25-0Relevant articles and documents
Method for preparing 2-bromoindole by using electrochemical micro-channel device
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Paragraph 0069-0073, (2021/01/24)
The invention provides a method for preparing 2-bromoindole by using an electrochemical micro-channel device, which comprises the following steps: assembling an electrochemical micro-channel reactiondevice, and dissolving indole compounds and bromine-cont
The facile synthesis of 2-bromoindoles via Cs2CO 3-promoted intramolecular cyclization of 2-(gem-dibromovinyl)anilines under transition-metal-free conditions
Li, Pinhua,Ji, Yong,Chen, Wei,Zhang, Xiuli,Wang, Lei
, p. 73 - 78 (2013/03/29)
2-Bromoindoles were readily prepared through a facile Cs2CO 3-promoted intramolecular cyclization of 2-(gem-bromovinyl)-N- methylsulfonylanilines in excellent yields under transition-metal-free conditions. This methodology could be extended to the synthesis of corresponding 2-chloroindoles. The reaction mechanism suggested that cyclization occurs through a key intermediate, phenylethynyl bromide, followed by cyclization in one-pot. The Royal Society of Chemistry.