141820-46-4

Upstream product

• 141820-42-0 {4-[2-(5-Methyl-2-naphthalen-2-yl-oxazol-4-yl)-ethoxy]-phenyl}-methanol 

Downstream Products

• 132646-53-8 5-{4-[2-(5-Methyl-2-naphthalen-2-yl-oxazol-4-yl)-ethoxy]-benzyl}-oxazolidine-2,4-dione 

Relevant academic research and scientific papers

Benzyloxazolidine-2,4-diones as potent hypoglycemic agents

A series of benzyloxazolidine-2,4-diones, containing oxazole-based side chains, were found to lower blood glucose levels in the genetically obese ob/ob mouse. Incorporation of a benzofuran structural element in these compounds provides greatly enhanced in vivo potency. The syntheses and structure-activity relationships for this series are detailed.