1418217-20-5Relevant articles and documents
Prolinethiol ether catalysis in an asymmetric michael reaction: Solvent-free synthesis of functionalized monohaloalkenes
Xia, Ai-Bao,Wu, Chao,Xu, Dan-Qian,Wang, Yi-Feng,Du, Xiao-Hua,Li, Zhao-Bo,Xu, Zhen-Yuan
, p. 1254 - 1259 (2013/04/10)
The organocatalytic Michael reaction of ketones with γ- monohalonitrodienes catalyzed by chiral prolinethiol ether under solvent-free conditions was developed. The described method represents a novel approach for accessing highly functionalized monohaloalkenes with α, β-stereocenters of up to >99% ee.