1418294-67-3Relevant academic research and scientific papers
Efficient enzyme-catalyzed synthesis of peptide secondary amides for use as serine proteinase inhibitors
Sergeev, Maxim E.,Voyushina, Tatiana L.,Sergeeva, Olga A.,Belozerskaya, Galina G.
experimental part, p. 58 - 66 (2012/09/07)
An efficient and straightforward approach toward enzymatic synthesis of secondary amides of peptides was developed. A number of peptide derivatives containing amide moiety at C-terminus was obtained via subtilisin catalysis in good yields under mild conditions. Biological activity of some peptamides is evaluated.
