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1418307-30-8

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  • 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-N-(4-trifluoromethyl-pyridin-2-yl)benzamide

    Cas No: 1418307-30-8

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1418307-30-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1418307-30-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,1,8,3,0 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1418307-30:
(9*1)+(8*4)+(7*1)+(6*8)+(5*3)+(4*0)+(3*7)+(2*3)+(1*0)=138
138 % 10 = 8
So 1418307-30-8 is a valid CAS Registry Number.

1418307-30-8Downstream Products

1418307-30-8Relevant articles and documents

Design and synthesis of novel substituted benzyl pyrrolopyrimidine derivatives as selective BTK inhibitors for treating mantle cell lymphoma

Ran, Fansheng,Liu, Yang,Chen, Xin,Zhuo, Huijun,Xu, Changqing,Li, Yuxia,Duan, Xiaoming,Zhao, Guisen

, (2021)

Ibrutinib, a potent irreversible Bruton's tyrosine kinase (BTK) inhibitor, was approved by the FDA for treating mantle cell lymphoma (MCL). Although ibrutinib exhibited excellent antitumor activity, it was associated with certain adverse reactions, with o

The compounds of structure containing conjugated zincon, its pharmaceutical composition and use thereof (by machine translation)

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, (2018/03/24)

The present invention relates to compounds having a structure containing conjugated zincon, its pharmaceutical composition and use, and in particular relates to the general formula (I) or a salt thereof to the compound represented by the, pharmaceutical compositions thereof, and its as BTK inhibitors and/or B cell activation inhibitor, for the prevention or treatment B cell activity with abnormal and/or the use of the BTK-related diseases. The compounds of lymphoma, breast cancer, liver cancer, colon cancer, gastric cancer, such as lung cancer and cervical cancer cell has better lethal effect, note has potential for the treatment of cancer and self-immune diseases related to potential. (by machine translation)

IMIDAZOPYRAZINE INHIBITORS OF BRUTON'S TYROSINE KINASE

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Paragraph 00144; 00153, (2017/05/30)

In some embodiments, the invention relates to a BTK inhibitor or a pharmaceutically acceptable salt, cocrystal, ester, prodrug, solvate, hydrate or derivative thereof, or to pharmaceutical compositions comprising these compounds and to their use in therap

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