14185-37-6

Basic information

• Product Name: N-cyclohexyl-2-methylaniline
• Synonyms: N-cyclohexyl-2-methylaniline;2-Methyl-N-cyclohexylaniline;N-(2-Methylphenyl)cyclohexan-1-amine
• CAS NO: 14185-37-6
• Molecular Formula: C₁₃H₁₉N
• Molecular Weight: 189.29666
• Mol File: 14185-37-6.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-cyclohexyl-2-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-2-methylaniline(14185-37-6)
• EPA Substance Registry System: N-cyclohexyl-2-methylaniline(14185-37-6)

Safety Data

• Hazardous Substances Data: 14185-37-6(Hazardous Substances Data)

Upstream product

• 95-49-8 2-methylchlorobenzene 
• 108-91-8 cyclohexylamine 
• 95-53-4 o-toluidine 
• 108-94-1 cyclohexanone 
• 88-72-2 1-methyl-2-nitrobenzene 
• 108-95-2 phenol 
• 101-84-8 diphenylether 
• 1205-39-6 N-phenyl-2-methylaniline 
• 95-46-5 2-methylphenyl bromide 
• 615-37-2 ortho-methylphenyl iodide 
• 108-85-0 1-bromocyclohexane 

Relevant articles and documents

Aryl-Diadamantyl Phosphine Ligands in Palladium-Catalyzed Cross-Coupling Reactions: Synthesis, Structural Analysis, and Application

Synthesis, temperature-dependent NMR structure investigation and utilization of a new, stable and easily accessible aryl-diadamantylphosphine ligand family is reported. The bulky and electron-rich phosphorus center of the ligand enhances the catalytic activity of palladium in cross-coupling reactions of sterically demanding ortho-substituted aryl halides. In our study, we demonstrated the synthetic applicability of the new phosphine ligands in Buchwald-Hartwig and tosyl hydrazone coupling reactions.

Synthesis method for converting lignin 4-O-5 model compound diaryl ether into nitrogen-containing compound

The invention discloses a synthesis method for converting lignin 4-O-5 model compound diaryl ether into a nitrogen-containing compound. According to the synthesis method, a diaryl ether compound andan amine compound are subjected to a heating reaction in a certain amount of a solvent (containing a certain amount of water) in an argon atmosphere (containing a certain amount of air) under the actions of a metal catalyst and sodium borohydride, such that the drug with the important physiological activity or the compound with the natural product skeleton containing nitrogen is formed by directlycoupling the C-O bond cut and the amine compound cross while the corresponding aromatic hydrocarbon is obtained. According to the present invention, the synthesis method has characteristics of simpleand easily-available raw materials, high conversion rate, important product and good yield, and has broad application prospects in the degradation and deep development and utilization of lignin.