141854-25-3

Basic information

• Product Name: 1,2-Diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]butane-1,4-diol
• Synonyms: 1-(4-(2-(DiMethylaMino)ethoxy)phenyl)-1,2-diphenylbutane-1,4-diol;1,4-Butanediol,1-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenyl-,(R*,R*)-;1,2-Diphenyl-1-[4-[2-(Dimethylamino) Ethoxy]-Phenyl] Butane-1,4-Diol
• CAS NO: 141854-25-3
• Molecular Formula: C26H31NO3
• Molecular Weight: 405.53
• Mol File: 141854-25-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 569.708 °C at 760 mmHg
• Flash Point: 298.349 °C
• Appearance: /
• Density: 1.138 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,2-Diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]butane-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]butane-1,4-diol(141854-25-3)
• EPA Substance Registry System: 1,2-Diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]butane-1,4-diol(141854-25-3)

Safety Data

• Hazardous Substances Data: 141854-25-3(Hazardous Substances Data)

Usage

General Description

1,2-Diphenyl-1-[4-[2-(dimethylamino)ethoxy]phenyl]butane-1,4-diol is a synthetic compound with a complex chemical structure containing phenyl, butane, and diol groups. It is commonly used in the field of organic chemistry as a reagent, catalyst, or intermediate in the synthesis of other chemical compounds. This chemical has potential applications in pharmaceuticals, agrochemicals, and materials science. The specific properties and uses of this compound are dependent on its unique molecular structure, making it a versatile and potentially valuable building block in chemical synthesis. Additionally, this compound may have biological activity due to the presence of the dimethylamino and ethoxy groups, making it an interesting target for further research in the field of medicinal chemistry.

InChI:InChI=1/C26H31NO3/c1-27(2)18-20-30-24-15-13-23(14-16-24)26(29,22-11-7-4-8-12-22)25(17-19-28)21-9-5-3-6-10-21/h3-16,25,28-29H,17-20H2,1-2H3

Upstream product

• 51777-15-2 (4-(2-(dimethylamino)ethoxy)phenyl)(phenyl)methanone 
• 104-55-2 3-phenyl-propenal 

Relevant articles and documents

POLYMORPHIC FORM OF TOREMIFENE CITRATE AND PROCESS FOR ITS PREPARATION

The present invention provides a polymorphic form of toremifene citrate and processes for its preparation. It also relates to an improved process for the preparation of the Z isomer of the toremifene base, free of E isomer, and its pharmaceutically acceptable salts.

Novel tri-phenyl alkane and alkene derivatives and their preparation and use

The invention provides novel compounds of the formula: STR1 wherein n is 0 to 4, R1 and R2, which can be the same or different are H, OH, alkoxy of 1 to 4 carbon atoms, benzyloxy or methoxymethoxy; R3 is H, OH, halogen, alkoxy of 1 to 4 carbon atoms, benzyloxy, methoxymethoxy, 2,3-dihydroxypropoxy or STR2 wherein m is 1 or 2, R6 and R7, which can be the same or different are H or an alkyl group of 1 to 4 carbon atoms, or STR3 can form an N-containing three-, four-, five- or six-membered heterocyclic ring; R4 is OH, F, Cl, Br, I, mesyloxy, tosyloxy, alkylcarbonyloxy of 1 to 4 C-atoms, formyloxy or CH2 R4 is replaced by CHO; R5 is H or OH; or R4 and R5 together form an --O-- bridge between the carbon atoms to which they are attached, and their non-toxic pharmaceutically acceptable salts and esters and mixtures thereof. Processes for the preparation of these compounds are described, and also novel pharmaceutical compositions containing them. These compounds exhibit valuable pharmacological properties as estrogenic, anti-estrogenic, and progestanic agents. They are also effective against oestrogen-dependent tumors. Certain compounds are useful as chemical intermediates for the preparation of pharmacologically active compounds of the invention.