14186-59-5 Usage
Uses
Used in Pharmaceutical Research:
1H-Pyrrole-3-carboxylic acid, 1,2,4-trimethyl-, methyl ester is used as a building block for the synthesis of various pharmaceuticals. Its versatile reactivity and potential biological activity make it a promising candidate for the development of new drugs.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1H-Pyrrole-3-carboxylic acid, 1,2,4-trimethyl-, methyl ester is utilized as a key intermediate in the synthesis of various agrochemicals, contributing to the development of effective pest control agents and other agricultural products.
Used in Organic Synthesis:
1H-Pyrrole-3-carboxylic acid, 1,2,4-trimethyl-, methyl ester is employed as a versatile building block in organic synthesis, allowing for the creation of a wide range of chemical compounds with diverse applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 14186-59-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,8 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 14186-59:
(7*1)+(6*4)+(5*1)+(4*8)+(3*6)+(2*5)+(1*9)=105
105 % 10 = 5
So 14186-59-5 is a valid CAS Registry Number.
14186-59-5Relevant academic research and scientific papers
Deacylation of Pyrrole and other Aromatic Ketones
Moon, M. W.,Wade, R. A.
, p. 2663 - 2669 (2007/10/02)
Ethyl 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylate (1a) reacts rapidly with ethylene glycol in refluxing benzene with p-toluenesulfonic acid or perchloric acid as a catalyst to give ethyl 3,5-dimethyl-1H-pyrrole-2-carboxylate (3) in high yield (96 percent).Various 2- and 3-acylpyrroles can be efficiently deacylated by using this procedure.Other ketones which undergo deacylation include phenyl(2-phenylindol-3-yl)methanone (19), 1-(5-methyl-1-phenylpyrazol-4-yl)ethanone (20), and 2,4-dimethoxybenzophenone.Certain pyrrole ketones where the acyl group is flanked by two ring methyl groups are also cleaved under acidic conditions by using ethanedithiol.
