1418944-45-2Relevant academic research and scientific papers
Synthesis, spectral and antibacterial studies on Ni(II) and Zn(II) complexes involving N -furfuryl- N -isopropyldithiocarbamate (f iprdtc) and Lewis bases: X-ray structure of [Ni(fiprdtc) (NCS)(PPh 3)]
Rani, Palanisamy Jamuna,Thirumaran, Subbiah,Ciattini, Samuele
, p. 106 - 116 (2014)
[Ni(fiprdtc)2] (1), [Ni(fiprdtc)(PPh 3)(NCS)] (2), [Ni(fiprdtc)(PPh3) 2]ClO4 (3), [Zn(fiprdtc)2] (4), [Zn(fiprdtc)2 (1,10-phen)] (5) and [Zn(f iprdtc)2 (2,2′-bipy)] (6) (f iprdtc=N- furfuryl-N-isopropyldithio- carbamate, 1,10-phen=1,10-phenanthroline and 2,2′-bipy=2,2′-bipyridine) complexes were prepared and characterized by elemental analysis, electronic, IR and NMR spectra and the structure of 2 was determined by single-crystal X-ray crystallography. UV-Vis spectral data of 1-3 are consistent with the formation of square planar complexes. IR spectra of the complexes show the contribution of the thioureide form to the structure. A single-crystal X-ray structural analysis of 2 proved four-coordinated nickel in a distorted square planar arrangement with a S2PN donor set. Significant asymmetry in Ni-S bond distances was observed in [Ni S1=2.1655(8); Ni S2=2.2120(8) A]. This observation clearly supports the less effective trans of SCN- over PPh3. The observed shielding in N 13CS2 chemical shifts of heteroleptic nickel complexes 2 and 3 when compared with homoleptic nickel complex 1 indicates the effect of PPh3 on the mesomeric drift of electron density toward nickel through the thioureide C N bond. The N13CS2 chemical shift of 5 and 6 are additionally deshielded compared with 4 owing to the increase in coordination number. Complexes were screened for in vitro antibacterial activity and significant activity has been found.
