141944-98-1Relevant academic research and scientific papers
Hantzsch reaction with 6-Aminouracil: Synthesis of novel tetrakis(6-Aminouracil-5-yl)methanes and bis(decahydropyrido[2,3-d:6,5-d']dipyrimidine-Tetraones) linked to aliphatic or aromatic cores via ether-Amide or ester-Amide linkages
Abdelmoniem, Amr M.,Abdella, Amna M.,Elwahy, Ahmed H. M.,Abdelhamid, Ismail A.
, p. 136 - 149 (2020)
One-pot three-component cyclo-condensation reaction of bis(aldehydes) containing ether-Amide or ester-Amide linkages with 6-Aminouracil in boiling acetic acid afforded tetrakis(6-Aminopyrimidine-2,4-diones) or bis(tetraoxodecahydropyrido[2,3-d:6,5-d']dipy
Microwave-assisted three component synthesis of novel bis-fused quinazolin-8(4H)-ones linked to aliphatic or aromatic spacer via amide linkages
Abdelhamid, Ismail A.,Elwahy, Ahmed H. M.,Fares, Ibrahim M. Z.,Mekky, Ahmed E. M.
, (2020/02/20)
A novel series of bis(tetrahydro[1,2,4]triazolo[5,1-b]quinazolin-8-ones) and bis(tetrahydrobenzo[4,5]imidazo[2,1-b]quinazolinones) containing amide linkages were regionselectively prepared via a three-component reaction of bis(aldehydes) with dimedone and
Efficient synthesis of novel bis(dihydropyrano[2,3-c]pyrazoles), bis(4Hchromenes) and bis(dihydropyrano[3,2-c]chromenes) with amide functionality
Abdella, Amna M.,Abdelmoniem, Amr M.,Butensch?n, Holger,Abdelhamid, Ismail A.,Elwahy, Ahmed H.M.
, p. 306 - 324 (2020/02/13)
A synthesis of novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles), bis(4H-chromene-3-carbonitriles) and bis(dihydropyrano[3,2-c]chromenes), which are linked to aliphatic spacers via amide linkages was achieved via multicomponent reactions (MCR) o
HEMIAMINAL-TAG FOR PROTEIN LABELING AND PURIFICATION
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Page/Page column 17, (2018/06/30)
The invention pertains to the synthesis, isolation, and characterization of hemiaminal for selective labeling of peptides, proteins, antibodies, and organic fragments with -C(=0) CH2NH2 and derivatives with -CH2NH2 group over -C(=0) CHRNH2 group (where R≠H). The invention also pertains to the method of single-site immobilization of proteins through N-terminus Gly on solid phase. The invention includes late-stage tagging of N-terminus Gly with an affinity tag, 19F NMR probe, and a fluorophore and a method for metal-free protein purification and isolation of analytically pure proteins.
Synthesis of novel macrocyclic Di- and tetralactams containing triazole subunits
Elwahy, Ahmed H.M.,Abbas, Ashraf A.,Kassab, Refaie M.
, p. 551 - 559 (2007/10/03)
The new macrocyclic di- and tetralactams 9, 15, and 16 were obtained in 16-24% yields by heating the appropriate bis-amines 7 or 8 with the corresponding bisaldehyde 5 or 14 in refluxing acetic acid under high-dilution conditions.
Synthesis of New Dibenzo Nitrogen-Oxygen Donor Macrocycles Containing Two Amide Groups
Lindoy, Leonard F.,Mahendran, Sumathi,Krakowiak, Krzysztof E.,An, Haoyun,Bradshaw, Jerald S.
, p. 141 - 144 (2007/10/02)
Four new nitrogen-oxygen, dibenzo macrocyclic ligands containing two amide groups have been prepared by combining a dibenzo-containing diamidodialdehyde with an appropriate diamine followed by reduction of the intermediate bis Schiff-base.The starting dib
